NTL Record

Title Pupillary movements during acute and chronic fatigue : a new test for the objective evaluation of tiredness.
Record ID 38907
Personal Name
Creator
Lowenstein, Otto; Feinberg, Richard; Loewefeld, Irene E.
Corporate Creator Columbia University. College of Physicians and Surgeons; Georgetown Clinical Research Institute
Publisher Civil Aerospace Medical Institute
Publication Date 19630400
Language English
Abstract Spontaneous pupillary movements in darkness were recorded in 1.healthy subjects of different ages when they were rested or fatigued, 2.chronically tired subjects without known neurological defects, and 3.patients with various neurological lesions. In some of the experiments, local or systemic drugs were used. While the pupils are large and quiet in darkness when the subject is alert, they oscillate under the influence of tiredness. Waves of spontaneous pupillary contraction and dilation accompany periods of increasing sleepiness and spontaneous arousal until, at the moment immediately preceding sleep, the pupils become very small. The mechanism of these movements was analyzed and a simple test described which allows the objective determination of the degree of acute fatigue in a given subject at a given time. In the light of these results, the concepts of 'normal' and of 'pathologic' fatigue were discussed.
Rosap ID dot:20737
Rosap URL https://rosap.ntl.bts.gov/view/dot/20737
TRT Terms Eye; Eye movements; Night vision; Vision; Physiological fatigue; Drowsiness; Sleep; Reaction time; Nervous system; Brain; Nerves; Age; Alertness; Drug effects; Nervous system diseases; Pathology; Physiological aspects; Human subject testing; Experiments; Case studies
General Subjects Pupil (Eye); Pupillometry; Night vision; Fatigue; Drowsiness; Sleep; Central nervous system; Brain; Nerves; Reflexes--Testing; Oscillations; Sphincters; Mydriatics; Age; Drugs--Physiological effect; Pathology
Classification NTL - AVIATION - AVIATION
Geographical
Coverage
United States
Report Number AM 65-9; DOT/FAA/AM-65/9
Resource type Tech Report
URL https://ntlrepository.blob.core.windows.net/lib/38000/38900/38907/AM65-09.pdf
Format PDF
Database NTL Digital Repository