| Title | Problems in aviation personnel : influence of a tranquilizer on temperature regulation in man. |
|---|---|
| Record ID | 38956 |
| Personal Name Creator |
Iampiertro, P.F.; Fiorica, V.; Dille, J.R.; Higgins, E.A.; Funkhouser, G.; Moses, R. |
| Corporate Creator | United States. Office of Aviation Medicine |
| Publisher | Civil Aerospace Medical Institute |
| Publication Date | 19660500 |
| Language | English |
| Abstract | The effects of a tranquilizing drug of the propaediol group, meprobamate, on thermal balance of men exposed to a cold (50F, 10C), hot (110F, 43.3C), or neutral (80F, 26.7C) environment have been investigated. Results show that a single dose of meprobamate (800 mg) has no effect on temperature regulation of men resting in a neutral environment. During exposure to hot or cold environments, however, the drug groups showed impairment in thermal balance. In the cold, heat production and core temperature of the drug group were lower than the placebo group. In the heat, only moderate elevations in the core temperatures of the drug group were detected. Possible physiological mechanisms responsible for these differences are discussed. |
| Rosap ID | dot:20783 |
| Rosap URL | https://rosap.ntl.bts.gov/view/dot/20783 |
| TRT Terms | Air pilots; Drug effects; Tranquilizers; Placebos; Physiological aspects; Temperature; Respiratory system; High temperature; Low temperature; Amines; Blood analysis; Thermal stresses; Human subject testing; Experiments |
| General Subjects | Air pilots; Body temperature--Regulation--Effect of drugs on; Tranquilizing drugs; Placebos (Medicine); Respiration; High temperatures; Low temperatures; Catecholamines; Blood plasma--Analysis; Thermal stresses |
| Classification | NTL - AVIATION - AVIATION |
| Geographical Coverage |
United States |
| Report Number | AM 66-14; DOT/FAA/AM-66/14 |
| Resource type | Tech Report |
| URL | https://ntlrepository.blob.core.windows.net/lib/38000/38900/38956/AM66-14.pdf |
| Format | |
| Database | NTL Digital Repository |