| Title | The effects of a tranquilizer on body temperature. |
|---|---|
| Record ID | 39045 |
| Personal Name Creator |
Higgins, E. Arnold; Iampietro, P.F.; Adams, Thomas; Holmes, D.D. |
| Corporate Creator | Civil Aeromedical Research Institute. Aeronautical Center |
| Corporate Contributor |
United States. Office of Aviation Medicine |
| Publisher | Civil Aerospace Medical Institute |
| Publication Date | 19631000 |
| Language | English |
| Abstract | Four young adult mongrel dogs were exposed twice untranquilized to each of three environmental temperatures: 4.4°C, 23.9°C, and 37.8°C and exposed twice tranquilized with 2.2 mg/Kg propiopromazine hydrochloride. Rectal temperatures were monitored and recorded continuously during two hour exposures. Little difference was noted in rectal temperature response for tranquilized and untranquilized animals at the 23.9°C exposure. Tranquilized animals showed a greater decline in internal temperature at and environmental temperature of 4.4°C than control and when tranquilized showed a rise in rectal temperature during heat exposure (37.8°C) while control animals showed a decline. These results indicate an impairment in both heat loss and heat conservation mechanisms in the tranquilized animals during thermal stress but little, if any alteration of temperature control at non-stressful ambient temperature. |
| Rosap ID | dot:20871 |
| Rosap URL | https://rosap.ntl.bts.gov/view/dot/20871 |
| TRT Terms | High temperature; Low temperature; Tranquilizers; Thermal stresses; Temperature measurement; Laboratory animals; Dogs; Testing; Temperature endurance tests |
| General Subjects | Temperature--Physiological effect; Body temperature--Regulation; Tranquilizing drugs; Low temperatures; High temperatures; Thermal stresses; Temperature measurements; Dogs as laboratory animals |
| Classification | NTL - AVIATION - AVIATION |
| Geographical Coverage |
United States |
| Report Number | AM 63-23; DOT/FAA/AM-63/23 |
| Resource type | Tech Report |
| URL | https://ntlrepository.blob.core.windows.net/lib/39000/39000/39045/AM63-23.pdf |
| Format | |
| Database | NTL Digital Repository |