| Title | Effects of an organophosphorus pesticide on reproduction in the rat. |
|---|---|
| Record ID | 39069 |
| Personal Name Creator |
Ryan, Leonard C.; Endecott, Boyd R.; Hanneman, Gerald D.; Smith, Paul W. |
| Corporate Contributor |
United States. Office of Aviation Medicine |
| Publisher | Civil Aerospace Medical Institute |
| Publication Date | 19700100 |
| Language | English |
| Abstract | The toxic effects of organophosphorus insecticides are commonly ascribed to cholinesterase (CHE) inhibition. A search of the scientific literature revealed the well-established fact that a number of chlorinated pesticides adversely affect reproduction in mice and rats. However, little is known about the effects of organophosphorus pesticides on reproduction. Disulfoton was selected for this study because it is a widely used organophosphorus insecticide for which the acutely toxic, nonlethal dose in rats has been established. |
| Rosap ID | dot:20892 |
| Rosap URL | https://rosap.ntl.bts.gov/view/dot/20892 |
| TRT Terms | Aviation medicine; Insecticides; Esters; Phosphorus; Pesticides; Rats; Laboratory animals; Biological reproduction; Brain; Physiological aspects |
| General Subjects | Aviation medicine; Pesticides--Physiological effect; Insecticides--Physiological effect; Rats as laboratory animals; Reproduction; Brain; Organophosphorus compounds; Cholinesterases |
| Classification | NTL - AVIATION - AVIATION; NTL - SAFETY AND SECURITY - Human Factors |
| Geographical Coverage |
United States |
| Report Number | AM 70-3; DOT/FAA/AM-70/3 |
| Resource type | Tech Report |
| URL | https://ntlrepository.blob.core.windows.net/lib/39000/39000/39069/AM70-03.pdf |
| Format | |
| Database | NTL Digital Repository |