| Title | Behavioral changes from chronic exposure to pesticides used in aerial application : effects of Phosdrin on the performance of monkeys and pigeons on variable interval reinforcement schedules. |
|---|---|
| Record ID | 39206 |
| Personal Name Creator |
Lewis, Mark F.; Mertens, Henry W.; Steen, Jo Ann |
| Corporate Creator | Civil Aeromedical Institute |
| Corporate Contributor |
United States. Office of Aviation Medicine |
| Publisher | Civil Aerospace Medical Institute |
| Publication Date | 19720800 |
| Language | English |
| Abstract | The need for study of behavioral difficulties resulting from exposure to pesticides is based upon reports of behavioral difficulties in aerial applicators following organophosphate poisoning and is underscored by a recent plane crash of a cropduster pilot in which prior exposure to several organophosphate pesticides was implicated. The present study examines effects on performance of pigeons and squirrel monkeys of Phosdrin (mevinphos), a cholinesterase-inhibiting pesticide not previously studied in the laboratory. Variable interval schedules of reinforcement were used with both food and water as rewards. A dose related decrease in response rate was observed with all animals. Decrements in behavior were observed at doses below which external symptoms of Phosdrin poisoning occurred, indicating the need for further investigation of the behavioral actions of pesticides. |
| Rosap ID | dot:21008 |
| Rosap URL | https://rosap.ntl.bts.gov/view/dot/21008 |
| TRT Terms | Aerial application; Pesticides; Drug effects; Behavior; Air pilots; Poisons; Esters; Laboratory animals; Monkeys; Birds; Experiments; Laboratory tests |
| General Subjects | Pest control baits--Aerial application; Pesticides; Drugs--Physiological effect; Human behavior; Air pilots; Poisons; Cholinesterase-inhibiting insecticides; Mevinphos; Birds as laboratory animals; Monkeys as laboratory animals |
| Classification | NTL - AVIATION - Aviation Energy and Environment; NTL - AVIATION - Aviation Safety/Airworthiness; NTL - SAFETY AND SECURITY - Aviation Safety/Airworthiness |
| Geographical Coverage |
United States |
| Report Number | FAA-AM-72-29; DOT/FAA/AM-72/29 |
| Resource type | Tech Report |
| URL | https://ntlrepository.blob.core.windows.net/lib/39000/39200/39206/AM72-29.pdf |
| Format | |
| Database | NTL Digital Repository |