| Title | Inhalation Toxicology: I. Design of a Small-Animal Test System; [and, Inhalation Toxicology:] II. Determination of the Relative Toxic Hazards of 75 Aircraft Cabin Materials |
|---|---|
| Record ID | 39310 |
| Personal Name Creator |
Crane, Charles R.; Sanders, Donald C.; Endecott, Boyd R.; Abbott, John K.; Smith, Paul W. |
| Corporate Creator | Civil Aeromedical Institute |
| Corporate Contributor |
United States. Office of Aviation Medicine |
| Publisher | Civil Aerospace Medical Institute |
| Publication Date | 19770000 |
| Language | English |
| Abstract | In an effort to further the cause of increased safety for those who ride in commercial aircraft, this paper presents a detailed description of the genesis of a small-scale, laboratory test system that utilizes small animals to evaluate the relative toxic hazard of combustion products generated by the thermal decomposition of nonmetallic materials. It includes: 1. a discussion of the concepts that led to the design; 2. detailed instructions for fabricating the system; 3. operating parameters and instructions for conducting a test; 4. an evaluation of the system's performance as determined by the testing of 75 aircraft cabin materials; 5. the utilization of animal response time as a basis for expressing relative toxicity; 6. and a discussion of the derivation of an inhalation dose concept that promises to be more useful than lethal concentrations. |
| Rosap ID | dot:21102 |
| Rosap URL | https://rosap.ntl.bts.gov/view/dot/21102 |
| TRT Terms | Air transportation crashes; Smoke; Aircraft cabins; Aircraft materials; Poisons; Polymers; Combustion deposits; Gas analysis; Thermal degradation; Toxicology; Pyrolysis; Fatalities; Laboratory tests; Laboratory animals; Rats |
| General Subjects | Aircraft accidents; Aircraft cabins; Poisons--Physiological effect; Gases, Asphyxiating and poisonous--Toxicology; Polymers; Combustion gases--Toxicology; Pyrolysis; Rats as laboratory animals |
| Classification | NTL - AVIATION - AVIATION; NTL - AVIATION - Aviation Safety/Airworthiness; NTL - SAFETY AND SECURITY - SAFETY AND SECURITY; NTL - SAFETY AND SECURITY - Accidents |
| Geographical Coverage |
United States |
| Report Number | FAA-AM-77-9; DOT/FAA/AM-77/9 |
| Resource type | Tech Report |
| URL | https://ntlrepository.blob.core.windows.net/lib/39000/39300/39310/AM77-09.pdf |
| Format | |
| Database | NTL Digital Repository |