| Title | Distribution of Paroxetine in Postmortem Fluids and Tissues |
|---|---|
| Record ID | 81825 |
| Personal Name Creator |
Lewis, Russell J.; Kemp, Philip M.; Johnson, Robert D. |
| Corporate Creator | United States. Department of Transportation. Federal Aviation Administration. Office of Aviation. Civil Aerospace Medical Institute |
| Corporate Contributor |
United States. Department of Transportation. Federal Aviation Administration. Office of Aviation. Office of Aerospace Medicine |
| Publisher | United States. Department of Transportation. Federal Aviation Administration. Office of Aviation. Civil Aerospace Medical Institute |
| Publication Date | 20150701 |
| Language | English |
| Abstract | Paroxetine is a selective serotonin reuptake inhibitor that is a commonly prescribed drug for the treatment of depression, obsessive-compulsive disorder, panic disorder, social anxiety disorder, premenstrual dysphoric disorder, and post-traumatic stress disorder. There are certain side effects associated with paroxetine use that could negatively affect a pilot's performance and become a factor in an aviation accident. Such side effects include nausea, drowsiness, insomnia, and dizziness. It has also been suggested that paroxetine use may increase suicidal behavior and suicidal ideation. |
| Rosap ID | dot:57174 |
| Rosap URL | https://rosap.ntl.bts.gov/view/dot/57174 |
| TRT Terms | Air pilots; Air transportation crashes; Blood analysis; Drugs; Fatalities; Forensic medicine |
| General Subjects | Forensic toxicology; Paroxetine; Gas chromatograph/mass spectrometer (GC/MS); Postmortem distribution |
| Geographical Coverage |
United States |
| TRIS Online Accession No |
1570602 |
| Report Number | DOT/FAA/AM-15/11 |
| Resource type | Tech Report |
| URL | https://ntlrepository.blob.core.windows.net/lib/81000/81800/81825/201511.pdf |
| Format | |
| Database | NTL Digital Repository |